Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes.
Published in Genome Res., 2017
Recommended citation: Newman JRB, Conesa A, Mika M, New FN, Onengut-Gumuscu S, Atkinson MA, Rich SS, McIntyre LM, Concannon P. (2017). "Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes." Genome Res.. 27(11).
This paper is about the substantial, and previously underrecognized, role for alternative splicing in the pathogenesis of autoimmune disorders and particularly for Type I Diabetes. Our findings highlight a substantial, and previously underrecognized, role for alternative splicing in the pathogenesis of autoimmune disorders and particularly for Type I Diabetes.